Staphylococcus aureus can be spread from person-to-person and infections often occur in multiple members of the same household. S. aureus can also exist on household surfaces for prolonged periods of time. The SHINE study is a comparative effectiveness trial to evaluate several decolonization strategies in patients with MRSA infection, their household contacts, and household environmental surfaces to interrupt transmission of S. aureus among household members and prevent S. aureus infections.
The central hypothesis of this trial is that an integrated approach of periodic personal and household environmental hygiene will reduce MRSA transmission in households and subsequently decrease the incidence of skin and soft tissue infections (SSTI).
Patients aged 2 months – 21 years with an active or recent skin infection caused by the Staph germ. All members of each household are asked to participate in the study.
The study team will come to the patient’s home for study visits 5 times over 9 months. The enrollment visit will last approximately 1.5 hours, and the following 4 visits will last approximately 1 hour.
Each participating household member will receive monetary compensation for their time totaling up to $120 for all 5 visits over the 9 month study.
Stephanie A. Fritz, MD, MSCI, Associate Professor of Pediatrics, Infectious Diseases, Washington University School of Medicine.